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In the novel, Uncle Petros is driven to despair and ultimately madness by his failure to prove Goldbach's conjecture.
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Some are driven to despair or suicide.
I see lots of people who are driven to despair by the behaviour of their neighbours.
Some animals, Braitman argues, are driven to despair — not some dumb, unthinking "animalistic" blankness but genuine spiritual emptiness.
Moderate reformers say they are driven to despair by what they see as inconsistencies in Washington's Middle East policy.
Unrecognised by the public, and not enough loved by the critics, he was driven to despair and madness.
The parents of the original, chronically poor and unable to feed their children, are driven to despair.
Vandeveld has written that he was driven to "despair" when his superiors rejected his ideas for getting Jawad home.
Far from being driven to despair by pestilence, it is as if they were spurred to assert the glory of life.
After being driven to despair by his degenerate life, Gray attempts to destroy the painting – which has grown hideous with his sins – but in doing so kills himself.
Kurdish village girls, exposed to television for the first time, were said to have been driven to despair by the discovery of a world in which women studied in universities, drove cars, and dated handsome men.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com