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When AEE788 is dosed as a single agent it is possible that one of the other active RTKs maintains PI3K/Akt signaling.
Taken together, these findings indicate that the activation and translocation of NF-κB by LPS is dose- as well as time-dependent.
The test compound or control substances (succinate, dimethyl succinate, monomethyl succinate, malonate, dimethyl malonate or dimethylsulphoxide (DMSO)) were dosed as indicated in each figure.
It was dosed as a suspension in dogs and found to have mediocre oral bioavailability with high variability.
The solvents were selected so to span a range of physicochemical properties, while K+ is an alkali cation typical of conventional electrochemical double layers which can reliably be dosed (as K atoms) to yield known low coverages on Pt(111).
Both nano and regular materials were dosed as suspension in vivo.
They were dosed as described above.
BG was dosed as nkat/g dw following the ratios of other proteins.
BALB/c female mice, six animals per group, were dosed as described in tumor xenograft model experiment.
Propofol was dosed as target controlled infusion (TCI) with a range of 2.2 to 4 mcg/ml and was supplemented by Sevoflurane, as needed.
The evolution of the dissolved nickel concentration during a methanogenic activity test was different when nickel was dosed as NiEDTA2− (Fig. 8B) or as NiCl2 (Fig. 8C).
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CEO of Professional Science Editing for Scientists @ prosciediting.com