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The first response of AR to androgen stimulation is dissociation from heat shock protein complex and translocation to the nucleus [10].
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A very promising candidate for this step is insulin dissociation from the receptor.
In both methods the critical point is the dissociation from the actual event and in fact both use the double disassociation technique.
Sex addicts don't just happen: the common factor is an early dissociation from intimacy.
Our results demonstrate that Akt does indeed regulate the interaction of HKII with mitochondria, but its main effect is to prevent dissociation from mitochondria upon glucose removal.
One possibility that explains our data is increased polymerase dissociation from the primer-template.
In response to stress, HSF1 is activated by dissociation from its complex with HSP90 and HSP70.
Taken together, these data support the notion that C/EBPβ phosphorylation is accompanied by dissociation from PRMT4/CARM1 and loss of the Mediator CDK8 module during hELA2 gene activation.
It is possible that dissociation from the nuclear periphery renders these genes "poised" and facilitates their activation by subsequent signals that may occur, e.g., during differentiation.
The systolic process is reversed: Ca2+ dissociation from cTnC induces a conformational rearrangement of the complex involving cTnI and cTnT, which immobilizes Tm on the thin filament (2).
A pre-requisite for the loss of histones from the nucleosome is the dissociation of DNA from the surface of the histone octamer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com