To date, all type II inhibitors were discovered by using structure-activity-guided optimization strategies.
New and improved catalyst compositions were discovered by using a total of seven generations each consisting of 92 potential catalysts.
A novel class of selective SHP2 allosteric inhibitors was discovered by using the powerful 'SBP'ADMETMET' and 'CDOCKER' techniques.
Mikhaylova managed to register her athletes for the Richmond races without being discovered by using an alias, said Megan Schultz of Sports Backers, which organized the events.
In this study, a series of novel small molecular CypA inhibitors have been discovered by using structure-based virtual screening in conjunction with chemical synthesis and bioassay.
The team found that, like Luke Skywalker's home planet of Tatooine, Kepler-1647b orbits two stars, making it the 11th such planet to be discovered by using the Kepler space telescope.
The new species were discovered by using a combination of sophisticated molecular analyses, including DNA sequencing; digital imaging, such as X-ray computed tomography; and statistical analysis of external and internal anatomy.
For exploring possible diuresis mechanism of E. lathyris, in this study, a potential diuresis related target, urea transporter B (UT-B), and its potential ligands were discovered by using bioinformatics method of "Inverse Docking".
A Russian drilling project designed to retrieve ice cores below the station was started in 1990, and a massive lake, spanning approximately 12,000 sq km (4,630 sq mi), was discovered by using satellite imagery and airborne ice-penetrating radar a few years later.
Very interesting patterns can often be discovered by using sound".
