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Similarly, Nr2e3 expression in the Nrl KO was almost abolished [12], suggesting that Nr2e3 expression is directly regulated by Nrl and indirectly regulated by Otx2.
Expression of cyp1a is directly regulated by the AhR signaling pathway.
Its recruitment to the DNA is directly regulated by the chromatin landscape, inclusive of chromatin compaction and epigenetic modifications.
At last, temperature is a major driven force in ionizing gas and creating plasma which is directly regulated with current density.
From a molecular point of view, Nell-1 is directly regulated by runt-related transcription factor 2 (Runx2/Cbfa1), a master regulatory gene controlling bone formation.
Our study indicates that survivin is directly regulated by IFN-γ.
While HIF-β is expressed constitutively, expression of HIF-α is directly regulated by low tissue pO2.
Mieap expression is directly regulated by p53 and is frequently lost in human cancer as result of DNA methylation.
The key criterion for a primary target gene is that its transcription is directly regulated by GR.
Its expression is directly regulated by MiTF through highly conserved M-box sequences in the promoter [12], [13].
Increasing amounts of Ro52 resulted in a dose-dependent increase in IRF7 ubiquitination (Figure 2B), indicating that this effect is directly regulated by Ro52.
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