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Although the causality between depression and pain relief is hard to establish, our findings suggest that depression is an important psychological factor in determining whether cancer patients will experience effective pain management, especially when depression is difficult to manage.
Another pattern I've seen is that managers will sometimes complain that one of their employees is difficult to manage.
2) The rise in numbers of emails is difficult to manage.
"It is difficult to manage a law firm with two principal locations," said Mr. Steir, whose company has specialized in representing law firms.
Their complexity and evolution is difficult to manage.
It is difficult to manage data centers with conflicting goals simultaneously.
"Could it come to a point where we say it is difficult to manage?
"All this does is make you seem like somebody who is difficult to manage".
The first is difficult to manage, in the face of the manifest differences across religions.
Gallbladder disease of patients with liver cirrhosis is difficult to manage [6].
It is difficult to manage extra-articular distal humerus fractures with locking intra-medullary nails.
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