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This is due to the fact that it is difficult to invert the nonsquare 4 2 acoustical plant matrix H.
The density is difficult to invert, which will have a deleterious influence on the estimation of Young's modulus.
JAGS may fail if the variance covariance matrix is difficult to invert (probably due to problems if the matrix is only borderline positive-definite), however, this issue can be solved by setting a very small initial value for the precision tau (see Additional file 1), such as 0.001.
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Such systems are difficult to invert with iterative techniques.
Very small delay differences lead to ill-conditioned (or even rank-deficient) Fisher information matrices, that are difficult to invert.
Without a control group implanted with a non-inverted version of this prosthesis, it is difficult to isolate the impact of inverting the bearing materials upon the severity of notching.
(1) The inverted NMR T2 distributions from the DP method depend on the estimated noise level which is difficult to estimate accurately.
However, it is clear that our CMV-driven pMF platform is more difficult to invert than our previously described tet-driven system (pCSkI + PB-OFF: ∼80% efficiency in HeLa) (Farruggio et al., 2012), so it is possible that a stronger-promoter platform would have produced a clear CT{8,8} TcT P3 × B3 recombination signal.
They can be difficult to find, but light corn syrup, also an invert sugar, makes a good substitute.
Fragile sites are usually associated with DNA sequences that are difficult to replicate and prone to form secondary structures, such as certain trinucleotide repeats (TNRs), AT rich sequences, inverted repeats, and sequences with the potential to form G quadruplexes.
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