Sentence examples for is difficult to formulate from inspiring English sources

β-carotene was used as a poorly water-soluble model substance that is difficult to formulate with conventional solid dispersion formulations.

Intelligibility varies so much with the speaker and the hearer, however, that it is difficult to formulate firm criteria on that basis.

It did not take Arthur long to discover that it is difficult to formulate a useful model in conventional mathematical terms.

It is difficult to formulate a distinct definition for each of these terms, because their use largely overlaps in the literature despite individual preferences.

But it is difficult to formulate the reductionist claim precisely.

It is difficult to formulate this point precisely, however.

Most invitees understand that guest lists are difficult to formulate, and that budgets, venues and large families can force tough choices.

Without support from top management, it will be difficult to formulate and implement market orientation and corporate social responsibility programmes.

Thanks to the architecture of the optimiser, a multi-objective gradient-based optimisation, which was difficult to formulate, has been proposed.

Instead of formulating an overall optimization problem, which would cover all possible decision variables at the price of being difficult to formulate and impossible to solve, we employ an approach based on discrete-event simulation.

Additional numerical examples are presented for which analytical methods are difficult to formulate and do not exist in the literature, in order to bring out the breadth of application of the finite element method.