Sentence examples for is difficult to align from inspiring English sources

Alignment of the TCP and R domains is unambiguous across taxa, however, the intervening region is difficult to align; therefore, we omitted ambiguous portions of this region from the alignment.

That is because it is difficult to align the interests of people who live in forests (now 20m in the Brazilian Amazon) with those of the rest of humanity.The best way of doing so involves a mixture of two ideas: establishing clear property rights over land and paying its owners not to cut down trees.

It is difficult to align chemical profiles measured with different types of microsensors, and it would thus be optimal if one sensor simultaneously can measure two or more parameters.

However, because of the lack of degrees of freedom in the positioning of the laparoscopic ultrasound probe, it is difficult to align an ultrasound imaging plane with the longitudinal section of a blood vessel in the liver.

"I'm cautious about the conclusions because the HLA system is so variable in living people," commented John Hawks, assistant professor of anthropology at the University of Wisconsin-Madison, US. "It is difficult to align ancient genes in this part of the genome.

However, Philippe has made the argument that Mreb and Hsp70 are very distant paralogs, so it is difficult to align them [ 27].

Moreover, conserved regions with ICS are difficult to align well by one single alignment.

Some sequences, particularly ribosomal genes such as 18S, are known to be difficult to align properly [ 98], and these alignment ambiguities can significantly affect phylogeny reconstruction [ 95, 99].

From the perspective of land plant alignments, matK is also problematic, as it was difficult to align seed plants with other land plants (e.g., the seed plant alignment took about two person days to complete and carefully check for the current small sample of taxa).

For example, the In 2L t proximal break point in D. melanogaster and D. simulans shows a large number of indel polymorphisms at the break point (Andolfatto and Kreitman 2000) and similar results are found for the In 3R P break point (Matzkin et al. 2005), suggesting that reads from such a rearrangement break point would be difficult to align to the reference with current-generation aligners.

Traditional internal alignment accuracy decreases as evolutionary distance increases; different sequences are difficult to align accurately.