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Thus, predicting mortality in diabetic patients is definitively needed in order to target aggressive prevention strategies to very high-risk patients.
This figure could well be offset by the potential to improve overall uptake of the immunoprophylaxis programme for RhD negative women carrying an RHD positive baby, as counselling and follow-up could be targeted at these women to try to improve anti-RhD immunoglobulin uptake when it is definitively needed.
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Additional attempts, aimed at better clarify the role of ENPP1 as a pathogenic factor predisposing to insulin resistance-related abnormalities and type 2 diabetes, are definitively needed.
Prospective studies are definitively needed in which PPG is specifically corrected early in the course of the disease.
23 Clinical and dose-adjustment studies of rilpivirine coadministered with rifabutin or rifampicin are needed before coadministration is definitively ruled out.
Like Grant, Sherman was convinced that the Confederacy's strategic, economic, and psychological ability to wage further war needed to be definitively crushed if the fighting were to end.
Unrelatedness between clones has been a key assumption in much modelling of drug resistance (e.g. [43] [45]) and in data analysis (e.g. [35], [46]) and it is an important question that needs to be definitively proved or disproved, presumably by analysis of a larger dataset and explicitly considering the threat posed by the presence of nulls.
Our studies suggest that I3C induces BRCA expression via an endoplasmic reticulum stress-like pathway, although this hypothesis needs to be definitively proved.
Novel IV formulations with favorable pharmacokinetics have been developed [ 201], but their use in clinical practice needs to be definitively assessed.
Nevertheless, the mechanism responsible for resistance of certain MRSA strains and MSSA strains towards PDT thus needs to be definitively clarified in the future.
However, as gauging the reliability of using a Likert question with people with dementia to obtain perceived difficulty was not within the scope of this study, this needs to be definitively addressed through future research.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com