Sentence examples for is critically regulated from inspiring English sources

Mcl-1 is a critical survival protein in a variety of cell lineages and is critically regulated via ubiquitination.

Meanwhile, there is a significant body of evidence indicating that occludin is important for the regulation of TJ structure and integrity and that this function is critically regulated by phosphorylation events [ 15, 16].

Developmental neuronal cell death is critically regulated by the pro-death protein Bax.

The UPR can activate the mitochondrial apoptotic pathway, which is critically regulated] by several members of the Bcl-2 family.

Purpose: Tumor cell migration and metastasis share many similarities with leukocyte trafficking, which is critically regulated by chemokines and their receptors.

In this study we demonstrated that functional polarization of M2 macrophages in vitro and in vivo is critically regulated by a transcription factor RBP-J that integrates signals from multiple input sources including the Notch signaling pathway.

Altogether our data suggest that, in conditional visuo-motor learning, the associations are critically regulated by the dorsal premotor cortex and the striatum, with additional brain areas contributing to specific aspects of the learning and performance of such associations.

The potential for NK activation was critically regulated by the peptide primary sequence.

Thus, eNOS activity and the cellular concentration of NO are critically regulated by mechanical forces imposed on smooth muscle.

Immunohistochemical analysis was also used for the detection of β-catenin, the levels of which are critically regulated by the Wnt pathway (see Introduction and references therein).

Furthermore, NPR-A gene transcription and guanylyl cyclase (GC) activity of the receptor are critically regulated by Ets-1 in target cells [32].