Exact(5)
Cellular functions and biochemical events are coordinately carried out by groups of proteins interacting each other in functional modules, and the modular structure of complex networks is critical to function [ 6, 8, 9].
Protecting a soldier's head from injury is critical to function and survivability.
This process can be applied to other drug targets in which conformational rearrangement is critical to function.
This translocation is critical to function of transcription factors that contain a regulatory cysteine in the DNA binding region, including nuclear factor-κB (NF-κB) [4], [5], [6], glucocorticoid receptor (GR) [7], [8], activator protein-1 [10] [11], [11], nuclear factor (erythroid-derived 2 -like 2 -like2) [12], [13], Hypoxia-inducible factor 1 alpha (HIF-1α) [14] and p53 [13], [16].
Therefore, in current models, the timing and amplitude of clock gene expression is critical to function (Forger and Peskin, 2003).
Similar(55)
For humans, identifying faces is critical to functioning in everyday life.
They possess an additional characteristic, the ability to remain stable at very high concentrations for long periods of time, which is critical to functioning in the eye because proteins in that part of the body cannot be repaired or replaced.
However, as low-energy states are naively expected to be critical to function, these observations pose important challenges.
By gathering gene expression data for a 52 × 52 matrix of different RNA-IN/RNA-OUT pairs, the authors were able to construct a statistical model to find sequence elements and predicted structural features that were critical to function.
This study adds to the existing gamut of aging literature, providing evidence that DMN function is critical to cognitive functioning in older adults.
The HPA axis is critical to homeostatic function and plays an essential role in mediating the body's stress response.
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