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To investigate the causes of differential IS abundance and distribution among Wolbachia genomes, we searched for potentially functional IS copies, defined as full-length copies with intact transposase genes.
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Before manufacturing the laboratory samples the characteristics of the free paths (depth and length) to be copied were defined in the field by comparing the radiographic results and the cracking framework, obtained from other studies made within the restoration project.
Nonfunctional IS copies are defined here as full-length copies with pseudogenized transposase genes or non full-length copies (i.e., trunon full-lengthnd fragments).
One such form is copy number variation (CNV), defined as a deletion, duplication or insertion of DNA sequence fragments longer than 50 base pairs in length [ 1].
Consequently, a copy is defined as secondary if there is at least one replica in the neighbourhood.
One of the mutational classes that contribute to neurodevelopmental disorders are copy number variations (CNVs), defined as >1 kilobase regions that harbor deletions or duplications of chromosomes.
Similarly to the previous period, the number of signal copies and the ratios (HER2/CEP17) were calculated for each probe Gene copies (> 6) or cluster formations (small clusters ~ 6 copies, larger clusters ~ 12 copies) were defined as amplified.
Gene copies (>4) or cluster formations (small clusters ~ 6 copies, larger clusters ~ 12 copies) were defined as amplified.
We cannot learn without mimicking (whether it's learning to write a paper or learning how to catch a football) — but the way copying is defined in legal terms obscures this fact.
Given a gene, a gene copy is defined as another sequence similar to the original one within the parameters used in this paper (see below), and the copy number refers to the number of gene copies that are estimated to exist for a given gene.
The score for this copy is defined as Score c (PIS) = -ln overall _ E - value pIS)) TIR signals of IS elements in the same IS group tend to be conserved, as shown in Figure 2 and Additional file 2, Figure S1.
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