How this rare cholesterol-depleted HDL particle is continuously generated from mature HDL at the artery wall is not entirely understood [ 6, 7, 8▪▪, 9, 10], leaving this and other important questions unanswered.
This is particularly relevant, for example, for miRNAs whose list is continuously growing (known mature human miRNAs are at present 2588, but they were only 313 about ten years ago), and the number of miRNA targets experimentally validated is only a minimal fraction (less than 2%%) of those numerically predicted.
The geometrical arrangements in the particular organ determine the way in which this occurs, but in general the consequence is that the meristem is continuously moving away from the maturing tissue as growth continues.
The register is continuously expanding and data is maturing.
RORα is continuously expressed in all mature ILC subsets.
Taken together, these data suggest that mature CML is continuously supplied by the COCs, whereas the initial B-ALL COC-population is lost in case of B-ALL.
But regulation is continuously changing.
(Radon is continuously replenished).
References are made to standards and standard guides which are continuously being developed as the field matures as a means for promoting more consistency in testing and therefore more comparability of published results.
Innovative technologies for cell patterning, preservation and interpretation are continuously being developed; when they all mature, cell arrays may become an efficient analytical tool, in a scope resembling that of DNA microarray biochips.
