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In fact, it could be more illuminating to consider associative overdominance not as a mechanism at all, but just as a side effect created by selection when it is constrained to operate mostly against homozygotes: an illusion of advantage for heterozygotes that, occasionally, concurs with some increase of neutral diversity.
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The theory of mixed embeddedness suggests that ethnic entrepreneurs are constrained to operate in a limited social, economic and institutional context, which influences the nature and success of the businesses undertaken.
As Hernando de Soto, the Peruvian economist, has lucidly and frequently explained, informal businesses are constrained to operate in very small markets, usually the local community; consequently they are unable to reap the rewards of productivity and competitiveness that stem from economic specialization in the wider marketplace.
Physical systems are constrained to operate according to the fundamental laws of thermodynamics.
A lot of companies used to be constrained to operating in one region in the country.
Yet Ms. Diaz is immediately able to operate in three dimensions, even if her character is constrained to two.
The most encouraging sign for journalism, although maybe an alarming one for business managers, is that we now see dozens of journalists, who were previously constrained to operating on their own sites, posting ever more material and links to places where their audiences might be.
"Because this asset class has a limited operating history, we expect the rating to be constrained to low investment-grade for the near future," the analysts wrote, predicting that the market would continue to grow rapidly.
Bush was constrained to take exception to this publicly.
Or can be constrained to do so.
In Drosophila studies, "bottom" was constrained to 0, while the "top" was not constrained.
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