Third, this paper also investigates the nature and sensitivity of this simple constraint equation to clear how frequently impacts have to be confirmed to reduce the measurement error.
Compounds 4a and 4b were confirmed to reduce the levels of HaloTag-fused tumor necrosis factor α (HaloTag-TNFα), HaloTag-fused cell division control protein 42 (HaloTag-Cdc42), and unfused HaloTag protein in living cells more potently than did BE04-linked compound 1b.
Several of the candidate genes tested were confirmed to reduce the growth inhibitory effects of n-butanol on E. coli.
Approximately 800 compounds were confirmed to reduce intracellular ATP levels in a dose-dependent manner in Mycobacterium bovis BCG.
A total of 2,900 compounds were tested, and 866 hits were confirmed to reduce intracellular ATP levels in a dose-dependent manner in M. bovis BCGMtbNar.
As a result, 0.5 and 1.0 mM EDTA were confirmed to reduce the intracellular ROS level increased with 1.0 mM RK.
In such a study, lovastatin was confirmed to reduce RAS protein expression, but inhibit AKT activity in KRAS-independent A549 and H460 NSCLC cells.
On the other hand, statins are confirmed to reduce risk of coronary events through decrease of plasma lipid levels and improving endothelial dysfunction via upregulation of endothelial nitric oxide and antioxidant activity, as well.
Since GDT has repeatedly been confirmed to reduce the length of hospital stay and postoperative complication rates, which per se determine long-term survival after major surgery [ 20], national authorities such as the National Institute for Clinical Excellence (NICE) in the UK facilitate top-down GDT implementation with accounting incentives.
If administration of CMV HIG is confirmed to significantly reduce the incidence of fetal infection following maternal seroconversion, then repeat serological testing at frequent intervals during pregnancy would be indicated to optimise timely detection of primary CMV, and enable prompt institution of treatment.
