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The genes we observed whose expression is concordant between two discrete tissues within the same individual are involved in several cellular pathways and processes.
The third observation described above suggests that, in order to yield a pathway expression profile that is concordant between independent datasets and predictive of a phenotype as well, a successful pathway-level aggregation method should not strictly depend on the overall direction of expression change of a pathway, as measured by the mean of z-scaled expression levels of its member genes.
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Finally for patient #3.3, 7 of the 11 genes were concordant between fresh and preserved blood.
Particularly, when the histological and molecular patterns were concordant between the primary and the relapse lesion, this was defined as a "true" intrapancreatic recurrence of the primary pancreatic ductal adenocarcinoma.
Antidepressant use was concordant between charts and data warehouse for 77% of the sample.
Of the 94 cases in our study, 80 (85.1 %) had a neurologic diagnosis that was concordant between the ED physician and the consultant neurologist.
The vast majority of cases in our study (85.1 %) had a neurologic diagnosis that was concordant between the ED physician and the final diagnosis, which reflects the ability of emergency physicians to assess and diagnoses neurologic complaints.
Among the 14 (14.9 %) discordant cases, 9 were given a neurologic diagnosis by the consultant that was a different than the one given by the ED physician (Table 5) and all were concordant between the consultant and the final discharge diagnosis.
In total, 96 of 116 (83%) measurements were concordant between the two methods (12 hypomethylation and 84 hypermethylation events).
In our analysis, 86 cis-SNP genotypes were significantly associated with the expression of the 20 genes whose expression was concordant between two independent tissue types.
Estimates of pairwise population differentiation between 23 populations were concordant between microsatellite-derived data and AFLP analysis of the same samples (r = 0.71, p<0.00001, 425 individuals from 23 populations).
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