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For instance, one may want to retrieve all the small tetrapyrrole molecules, that is compounds that contain four pyrrole rings and with weight less than a threshold value.
Similar rules have been derived for inhibitors, that is compounds that contain alkylaryl ethers, aromatic amines, and tertiary aliphatic amine groups are likely to be P-gp inhibitors.
These compounds represent an important addition to the existing classes of perfluorocarbons, that is, compounds that are composed only of the two types of atoms, carbon and fluorine.
"False positives", that is compounds that appear to bind the target protein well on the bead but display poor, if any, binding to the target protein in solution, are very common in this kind of screening experiment.
Many biogenic small molecules function at multiple levels, making it difficult and often artificial to differentiate between "metabolites", that is, compounds that are part of primary metabolism, and "secondary metabolites", that is, compounds not necessarily required for metabolic functioning.
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The main entities in the ChEBI database are compounds that are stored in the COMPOUNDS table.
Photoinitiators are compounds that break down into free radicals upon exposure to ultraviolet radiation.
Around palatial embassies were compounds that included schools, churches, and hospitals for the various nationalities.
Flavour enhancers are compounds that are added to a food in order to supplement or enhance its own natural flavour.
For example, acids are compounds that produce H+ ions (protons) when dissolved in water to produce aqueous solutions.
Thiosemicarbazones are compounds that contain the –NHCSNHN=C< linkage group.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com