Subsequently, the degree to which noise acts as the pathogenesis of sleep disturbance in ICU remains unclear, although it is commonly reported as an issue by survivors of critical illness.
The significance of the discordance between IHC-positive tumours and p53 mutation is unclear, although it is commonly reported (Gao et al, 2000; Babjuk et al, 2002; Doak et al, 2003).
Although the precise mechanism is unclear, insulin resistance is commonly accompanied by central (visceral) obesity, which, by elevating levels of free fatty acids in serum, may provoke insulin resistance and disrupt lipid metabolism.
It is presently unclear whether p27Kip1 is commonly a direct Erk target in CRC cells with high Erk activity, although phosphorylation of p27Kip1 by Erk1/2 in CRC has been suggested and complex formation of endogenous p27Kip1 and Erk1/2 was detected in LoVo cells by co-immunoprecipitation [ 20].
The latter effect is commonly observed in response to FXR activation, and it is still unclear whether it holds any potential for detrimental side effects in humans.
Stomatitis is commonly observed with other angiogenesis inhibitors, although the underlying mechanism remains unclear (Eskens and Verweij, 2006).
In this study, EBV infection is commonly observed in nasal NK/T lymphoma, but its oncogenic mechanism remains unclear.
It is unclear whether Ms. Worrell had such a medication, but Tramadol is commonly prescribed for arthritis.
The infrapatellar fat pad (IPFP) is commonly resected during knee joint arthroplasty, but the ramifications of doing so are unclear.
Although NNI is commonly used, the appropriate threshold for the balance of benefits and harms remains unclear.
