Sentence examples for is capable of repressing from inspiring English sources

Even so, these results and the fact that increasing amounts of Tbx3 causes a gradual decrease in the promoter activity of PTEN imply that Tbx3 is capable of repressing PTEN and that this repression is specific.

To ensure that H3K27 trimethylation is limited only to the repressed target, PRC2 is capable of repressing its own enzymatic activity.

Myc is capable of repressing its own gene, and this auto-repression is disrupted in all cancer cell lines tested [14], [15].

Similarly, the GTG3A GR mutant, which contains three mutations within the DBD, preferentially recognizes a thyroid hormone response element rather than GREs, yet is capable of repressing NF-κB-driven transcription27.

Together these results show that SDF1 is capable of repressing fgf20a expression during the regeneration process.

In addition, SALL1, another SALL gene family member, is capable of repressing transcriptional activity.

Among these compounds, only gastrodin was capable of repressing transplanted H22 ascitic hepatic tumor cell growth in vivo with low toxicity.

However, both Hes-1 [13][14] and Neurog3 itself [15] are capable of repressing Neurog3 expression in endocrine progenitors and it has been proposed that induction by Neurog3 of a putative downstream repressor may participate in this negative autoregulatory loop [15].

Because methylated DNA binding proteins or activities are capable of repressing reporter genes by recruiting histone deacetylase activity, the loss of HDAC due to loss of mp66α should result in a DNA methyltransferase knockout phenotype.

Research using breast cancer cell lines suggests that dietary phyto-oestrogens are capable of repressing EGF receptor activity.

Interestingly however, although Tbx3 was capable of repressing EP-PTEN and CP-PTEN, the deletion mutant was not repressed by Tbx3.