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An insertion sequence (IS) is a bacterial transposable element that is capable of inserting a new copy of its sequence elsewhere in the genome [ 33].
Life on Earth proceeds in an arc — one that began with the big bang, and evolved to the point where a smart teenager is capable of inserting a gene from a cold-water fish into a strawberry, to help protect it from the frost.
They did this by making small holes in the cell walls of individual bacteria and introducing pieces of special DNA, called transposons, through the openings.A transposon is capable of inserting itself more or less at random into another piece of DNA.
It has been previously reported that YidC alone is capable of inserting E. coli SecE, a SecE with multiple TMs, into the membrane [32].
In the first set of experiments, we determined whether each hydrophobic domain of the TPC is capable of inserting into the membrane in isolation.
It represents a thermodynamically impressive feat if the BAM complex is capable of inserting into the outer membrane an autotransporter with the huge passenger domain prepositioned on its outer surface (Jain & Goldberg, 2007; Ieva et al., 2008).
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In 1932, a preadolescent Ceylonese female was documented by British scholars of Tamil mysticism as being capable of inserting into her mouth and down her esophagus both arms to the shoulder, one leg to the groin, and the other leg to just above the patella, and as thereupon able to spin unaided on the orally protrusive knee at rates in excess of 300 r.p.m.
This simulator can be used for two purposes: one for training novice physicians in the correct manipulation and the other for physician certification which will help determine if they are capable of inserting the implant in vivo.
In this context it is interesting to note that also many other short, highly cationic and hydrophilic peptides, including the voltage sensor of K+ channels, are capable of inserting and in some cases even passing membranes [20] [22].
Class 1 integrons are capable of inserting, excising and rearranging gene cassettes by a site-specific recombination mechanism.
Due to their disruptive nature, TEs are capable of inserting into multiple sites of a gene, creating a series of TE tagged mutation lines [ 6].
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