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The Church Fathers were rightly convinced that ordinary human suffering is better validated through the orthodox Christian version of the Jesus story: an ordinary man martyred by his enemies.
The PSI is better validated for assessing patients with a low mortality risk who may be suitable for home management rather than for those with severe CAP at the time of hospital admission [ 18].
As a cross-sectional and single-centered study, its main strength involved the multiple groups including healthy controls which enabled the identification of risk factors for different types of depression and the utilization of 3.0T MRI and SWI which is better validated for the identification of microbleeds than traditional T2-GRE series [ 30].
In Tromsø 4 and 5, serum creatinine was analyzed by a modified Jaffe reaction, but since creatinine-based estimation of GFR is better validated for enzymatic creatinine measurements, 111 plasma samples from Tromsø 4 and 142 samples from Tromsø 5 were thawed and reanalyzed with an enzymatic method (Modular P/Roche).
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So Dr. Hayworth urged Dr. Fahy to find some way for his work to be better validated.
First, the different devices for CGM need to be better validated in terms of accuracy and reliability.
Current and new biomarkers need to be better validated in the field and by studying animal models.
Third, the sensitivity, specificity, and variability of biomarkers need to be better characterized and they must be better validated as predictors of disease risk.
Theoretically, it is better to validate every one miRNA predicted computationally for some further study on its regulation function, for a different nucleotide may influence the function of it.
If users have a list of genes they are interested in, and seven of them are on our list, it is better to validate own genes of interest using our higher-ranked genes.
Therefore, it would be worthwhile to examine in future studies whether it is better to validate the TTO against individualized measures of personal preferences, such as the SEIQOL [ 19, 20] or MACTAR [ 21].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com