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Psn is best characterized for its role in early onset familial forms of Alzheimer's disease (FAD).
Among the ruminococci, cellulose digestion is best characterized for R. flavefaciens [ 15, 16].
This family is best characterized for its association with Hsp90-steroid hormone receptor complexes containing client proteins such as the glucocorticoid, estrogen, progesterone, and androgen receptors [ 27- 30].
While kinesin-1 is best characterized for such activities (Navone et al., 1992; Straube et al., 2006; Jolly et al., 2010), dynein may contribute as well.
To date, three members are known, designated as JAM-A to -C (or JAM-1 to -3), whereas JAM-A is best characterized for its role in leukocyte diapedesis.
Natriuretic peptide signaling is best characterized for its role in cardiovascular homeostasis; however, most of the gastrointestinal tract has been described as a site of production of atrial natriuretic peptide (ANP).
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The conserved maturation phosphorylations have been best characterized for conventional PKC isozymes and are described.
For the Type I cytokine receptors to which the G-CSFR belongs, endocytosis and degradation have been best characterized for the growth hormone receptor (GH-R), interleukin-2 receptor (IL-2R), and the erythropoietin receptor (EpoR) [14] [19].
Mammalian Tim has been best characterized for its function in monitoring replication fork stability in S phase, but other functions of Tim can not easily be explained by its intra-S phase functions alone.
In mammals, D-type cyclins bound to Cdk4 or Cdk6 are best characterized for their functions during cell cycle progression, but several reports have shown additional roles, in particular the regulation of multiple transcription factors by direct binding [50].
The structural biology of this process has been best characterized for the influenza hemagglutinin, and paramyxovirus fusion (F) protein, for which the pre-fusion and membrane fusion pH structures have been determined by X-ray crystallography [4], [11], [12], [39], [40].
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