The implications of mutational subtype for both prognostic and predictive value are being increasingly understood.
In prokaryotes, the field is developing and the role of different DNA binding proteins in organized DNA structures are being increasingly understood with interesting manifestations [4].
The pathways that underlie tumour progression, invasion and resistance to treatment in each clinical state are being increasingly understood, and novel biologic agents that target these pathways are in development or are now available for clinical testing.
This theory was used as it is being increasingly advocated as a means to understand implementation processes and enhance the implementability of interventions [ 17, 24].
Drosophila melanogaster models are being increasingly used to better understand the patho-physiology of human diseases.
In addition to primary tumors, patient-derived samples grown in mouse xenograft (PDX) models are being increasingly used in pre-clinical settings to understand tumor biology and therapy response (Huynh et al., 2011; Morton and Houghton, 2007).
Conservation of biodiversity and natural resources is widely agreed as a global priority, not least because it is increasingly understood to be linked with efforts to improve well-being (Hassan et al. 2005).
"It is increasingly understood that Greece is a very unique case," added a European diplomat.
However, disaster risk is increasingly understood to be complex and multifaceted (involving hazard, exposure, vulnerability, and capacity), with interdependencies that may be overlooked and cause cascading effects over time and space (Gill and Malamud 2014, 2016).
