Complete resolution of the 16 ST was achieved by inclusion of both lipL41 and rpoB loci in the original concatenated sequence of each strain, Figure S2 F. The MLST scheme proposed by Thaipadungpanit and colleagues is based on loci from seven housekeeping genes and identified 109 unique ST among 263 isolates from either L. interrogans or L. kirschneri [17].
Expression of the ISG and PAG genes is known to be under transcriptional control (Haenni et al., 2009; Leung et al., 2011), which at least for PAG is based on locus-specific termination or elongation control.
Investigation of single nucleotide polymorphism (SNP) loci between Miyazakimochi and Bikei 22 was based on loci between Nipponbare and Koshihikari (Nagasaki et al. [2010]).
In this ROC analysis, which is based on 5718 loci in 59 samples, there were in total 150 162 CN = 0 (female) loci out of 305 502 loci.
In this ROC analysis, which is based on 68 966 loci in 59 samples, there were in total 2 000 014 CN = 1 (male) loci out of 4 068 994 loci.
The method employs a three-axis CNC milling machine equipped with suitable ball-end cutter and is based on the locus-tracing concept.
In conclusion, we demonstrated CSD in C. rubecula, and our laboratory data suggest that it is based on two loci.
While our laboratory studies suggest that CSD in C. rubecula is based on two loci – a scenario that should reduce diploid male production – 8 13% of diploid adults were male in a field population in Minnesota.
Exposures to insecticide concentrations that lie within the distribution of viability tend to produce resistance that is based on multiple loci, each of small effect (McKenzie et al. 1992).
The second approach to detect differential transcription is based on observing loci in the reference genome at which reads from the two datasets align with different depth of coverage (after appropriate normalization for differing gene expression).
However, it is based on a single locus in the genome only and clustering of S. aureus isolates based on spa-data is complex.
