"The whole science structure in the previous regime was based on isolating groups of scientists and telling them exactly what to do, without access to outside scientific groups," Dr. Shahristani said in an interview at his home in Baghdad.
Attempts to modulate phage pharmacokinetics were based on isolating long-circulating mutants of phage lambda [ 56].
Hence, definitive structure elucidation of such metabolites would have to be based on isolated compounds and required a formidable analytical effort.
In order to achieve a high yield of protein for analysis, mammalian expression systems tend to have been based on isolated, high expression stable cell lines [ 21].
The battery of traditional coagulation tests, which include prothrombin time, partial thromboplastin time, thrombin time, factor assays, and platelet function studies are based on isolated, static end points of standard laboratory tests [ 14].
In contrast to the traditional coagulation tests, which are based on isolated, static end points of standard laboratory tests, TEG takes into account the interaction between the clotting cascade and platelets in whole blood.
The criterion for intermediate susceptibility was based on isolates growing within one-fold dilution higher than the MIC value.
The incidence of invasive pneumococcal disease was based on isolates collected by The Netherlands Reference Laboratory for Bacterial Meningitis, a "laboratory-based surveillance system that collects nationwide pneumococcal isolates from blood and cerebrospinal fluid" and represents 25% of the Dutch population [ 13].
Cluster designation was based on isolates showing ≥80% relatedness.
However, depending on the study design, the expression may be based on isolate, patient, episode and/or resistance phenotype [ 46].
