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Galileo considered it "probable that this method is the same that Archimedes followed, since, besides being very accurate, it is based on demonstrations found by Archimedes himself".
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The diagnosis is based on demonstration of larvae in fresh faeces, which is best made by Baermann technique.
Traditionally, diagnosis is based on demonstration of spirochetes in blood films taken during the acute febrile period.
The test is based on demonstration of the presence of agglutinin (antibody) in the serum of an infected patient, against the H (flagellar) and O (somatic) antigens of Salmonella enterica serotype typhi, paratyphi A and paratyphi B, during the acute and convalescent period of infection [ 10].
"The transition will be based on demonstration of capacity rather than a specific time table," the document reads.
The diagnosis of VL was based on demonstration of leishmania parasites in bone marrow smears.
Diagnosis of empyema thoracis was based on demonstration of frank pus upon pleural fluid aspiration prior to admission.
This notion was based on demonstration of low ascorbate reserves in cancer patients, and later on results of clinical trials where survival time of cancer patients was prolonged by ascorbate supplementation (Cameron and Pauling 1976, 1978).
Introduction of routine use of novel biomarkers should be based on demonstration of a benefit when they are applied to a target patient population; hence, it is critical that these questions be addressed before procalcitonin is introduced as a screening tool in patients undergoing liver transplantation.
Current guidelines recommend that a diagnosis be based on demonstration of invasion by tumor cells [ 3]; however, not all patients are able to undergo invasive procedures to obtain a biopsy, and even when tissue is obtained diagnosis may still be difficult [ 4].
Diagnosis of this obligate intracellular bacterium is based on the demonstration of the microbe or microbial DNA in tissue specimens or faecal samples, or the demonstration of L. intracellularis-specific antibodies in sera.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com