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We argue here that the present analysis paradigm in quantitative genetics is at its limits in regards to unraveling complex traits and it is necessary to re-evaluate the direction that genetic research is taking for the field to realize its full potential.
The Astra has grip to spare, but when the overmatched engine is at its limits in corners, the tires still aren't breaking a sweat.
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Munich has said that it is at its "limit", after the refugee crisis has sent a huge influx of migrants into southern Germany.
"It could be that the biosphere is at its limit but we cannot tell that at the moment".
"Our patience is at its limit.
By that estimate, the jobless rate is at its limit.
But transmission is at its limit because some transmission lines are saturated.
However, with the 1 min temporal resolution coupled to the small (20 50 μM), rapid decreases in brain glucose, the temporal resolution of rsMD is at its limit.
Keep in mind: Some commercial steamers heat up the milk so quickly that you'll need to remove the milk from the steamer about 10º F before it's at its limit in order to keep it from scalding.
In January, Ikea said the appetite of western consumers for home furnishings had reached its peak and consumption of many familiar goods was at its limit.
Woodcrest, for instance, has been at its limit of 600 families for two years, and this summer 25 families are on the waiting list.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com