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There is considerable evidence, both in humans and animals that IFN-γ production is necessary for protective immunity against mycobacterial disease [18] [21] and successful chemotherapy of TB is associated with augmented IFN-γ production [22] [24].
Increased pro-inflammatory HDL in SLE is associated with augmented atherosclerosis [ 67].
Collectively, data indicate that CD36 deficiency is associated with augmented sub-retinal deposits.
Therefore, the exaggerated LV dysfunction in old mice is associated with augmented myocardial injury.
Thus, increased invasiveness is associated with augmented M2 polarization in the regional lymph nodes.
In addition, successful induction of apoptosis by chemotherapy and radiation is associated with augmented expression of Bax [ 54].
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These effects were associated with augmented intestinal MPO activity and oxidative damage such as an elevation of MDA production and a depletion of enzymatic and non-enzymatic antioxidants.
While improved glycemic control/insulin sensitivity has been associated with augmented cardiac function in pharmacologic studies, studies on dietary intervention are scarce.
There is evidence that Ca2+ desensitisation contributes to septic shock: in a rat model, acute endotoxaemia was associated with augmented MLCP activity and reduced sensitivity to an α1-adrenergic agonist [10].
The enhanced cytotoxicity of ATO + bortezomib was associated with augmented STAT3 inhibition and JNK activation, up-regulation of Bim, p21, p27, p53 as well as down-regulation of Bcl-2.
Such post-pubertal DA receptor alterations in the NAcc may be associated with augmented locomotor responses to the higher dose of amphetamine that we observed in adult NHL rats.
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