The instrument had not been translated into German before or validated for use among German-speaking women, nor have the results of the tool been assessed specifically for the administration directly after birth.
To test this, we applied a previously described biochemical assay using surface biotinylation followed by cleavage by the membrane-impermeant reducing agent MESNA [14], [15], which allows stability of the internalized receptor pool to be assessed specifically.
Descriptive statistics were assessed, specifically the geometric mean, for the parasitemia results.
The identification of discrepant threshold levels also suggests that the optimum cut-off value should be assessed specifically for each centre and assay [ 19].
As a minimum requirement, each patient included in a pain trial should be assessed specifically for pain and given a simple pain diagnosis.
Eight functional categories are assessed specifically by the HAQ: dressing and grooming, arising, eating, walking, hygiene, reach, grip, and common daily activities.
However, productivity losses should be assessed specifically for the disease to avoid overestimations of the role of the disease on indirect costs of lost productivity.
The consequence of such findings is that the potential utility of predictive biomarkers cannot be assumed to be generalizable for a given agent and must be assessed specifically in each tumor type and in each treatment setting.
However, the latitude for non-adherence to imatinib needs to be assessed, specifically if a threshold, tipping point, or tipping range exists below which risk of impaired response accelerates.
In this article, the predictive performance and validation of the model were assessed specifically by estimating the model from data up to 12 weeks and evaluating HbA1c predictions at end-of-trial (week 24 28).
