But for many people, the core of the immigration question – and one which I fully accept is a substantial issue – is immigration from non-European countries especially when from different cultures in which assimilation and potential security threats can be an issue.
Dale Ho, director of the ACLU's voting rights project, questioned Hans von Spakovsky, a former Justice Department official and member of the Presidential Advisory Commission on Election Integrity, who is one of the most prominent people arguing that noncitizen voter registration is a substantial issue.
Illicit drug use for recreational purposes is a substantial issue within Western society and causes significant health issues.
The informed and shared decision making between doctors and patients is the substantial issue in the ideal style (Thistlethwaite and Van der Vleuten 2004).
"One reaction is that these statues aren't a substantial issue, it's just symbolism," Brundage says.
This is not a substantial issue for linear normalization, which is mostly driven by a large contrast change at the outside boundary of the brain, but the blurred internal structures could easily confuse high-dimensional non-linear registration [21].
"So when you have 500 or 1,000 people who are misallocated, it's a fairly substantial issue.
