Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
is altered with
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "is altered with" is not correct in standard written English.
It may be intended to convey a change or modification involving something, but the construction is awkward and unclear. Example: "The document is altered with new information, making it more accurate."
⚠ May contain grammatical issues
Science
News & Media
Academia
Wiki
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
60 human-written examples
Conceivably therefore, if Ca2+ release from ER is altered with aging, this alteration may develop in parallel with altered Ca2+ influx (Clodfelter et al., 2002).
Science
These studies suggest that the contribution of the release of calcium from smooth endoplasmic reticulum calcium stores is altered with age through a combination of altered ryanodine receptor levels and modulation of these receptors by neuronal nitric oxide containing neurones.
Science
These results may suggest, however, that the cellular regulation of cholesterol metabolism is altered with ageing and could either involve abnormal regulation of cellular cholesterol export or altered production intracellularly [ 43, 48].
Further, the conventional sliding surface is altered with fractional order dynamics.
To determine whether the level of pigment epithelium-derived factor (PEDF) in the aqueous humor is altered with age.
Neurovascular coupling, the tight co-regulation of neuronal activity and structural and functional aspects of the cerebral vasculature, is altered with aging22.
Science & Research
To establish whether in diabetic patients with peripheral artery obstructive disease (PAOD) vasa vasorum (vv) neoangiogenesis is altered with increased arterial damage.
As in recent summers the stage configuration at Avery Fisher is altered, with the platform thrust into the hall and audience seating behind and to the sides of the ensemble.
News & Media
Among the effects that can arise from choline deficiency, Balskus said, are changes in DNA methylation, a process in which the activity of a DNA segment is altered with the attachment of a methyl group.
Academia
ACE2, a protective monocarboxypeptidase, responsible for conversion of Ang II to Ang1 7, opposes the deleterious effects of RAS pathway but how its expression is altered with blockade of AT1R and AT2R is not yet known.
Science
In type 1 diabetes the circulating IGF-system is altered with low IGF-I and changes in levels of IGF-binding proteins (IGFBPs) which may be of importance for the development of diabetes complications.
Expert writing Tips
Best practice
Avoid using "is altered with" in formal writing. Opt for more precise and grammatically sound alternatives such as "is modified by" or "is changed by" to improve clarity.
Common error
The phrase "is altered with" often incorrectly uses 'with' to indicate the agent of change. 'With' typically describes accompaniment, while 'by' correctly indicates the cause or means of alteration. Use "is altered by" to specify what is causing the alteration.
Source & Trust
79%
Authority and reliability
2.8/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "is altered with" functions as a passive construction indicating a state of change. However, it's often grammatically incorrect because 'with' typically denotes accompaniment rather than causation. Ludwig's analysis suggests using more precise alternatives.
Frequent in
Science
46%
Wiki
10%
News & Media
7%
Less common in
Academia
6%
Formal & Business
0%
Reference
0%
Ludwig's WRAP-UP
In summary, while the phrase "is altered with" appears frequently across various sources, including science, news, and general web content, Ludwig AI identifies it as grammatically incorrect. The more appropriate phrasing is "is altered by", as 'by' correctly indicates the agent of change, whereas 'with' implies accompaniment. To enhance clarity and grammatical accuracy, particularly in formal writing, consider using alternatives such as "is modified by", "is changed by", or "is affected by". These alternatives ensure that your writing is both precise and grammatically sound.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
is modified by
Focuses on the agent causing the change, offering a direct and grammatically sound alternative.
is changed by
Implies a transformation caused by an external factor, similar to modification but more general.
is affected by
Highlights the impact of something on the subject, showing a cause-and-effect relationship.
is influenced by
Suggests a more subtle effect, where the subject's nature or behavior is guided or swayed.
is transformed by
Emphasizes a significant change in form or nature, often implying a fundamental alteration.
is adjusted due to
Indicates a deliberate alteration to accommodate a specific factor or condition.
is adapted to
Implies a modification to suit a new purpose or environment, focusing on functionality.
is revised in light of
Suggests that new information or considerations led to a reevaluation and subsequent change.
is reworked because of
Indicates that alterations are made for improvements. The focus is on a creative task.
is converted into
Highlights a complete change from one thing to another. A transformative alteration.
FAQs
What's a grammatically correct way to express that something has been changed?
Instead of "is altered with", consider using phrases like "is modified by", "is changed by", or "is affected by" depending on the specific context.
Is "is altered with" considered formal English?
No, "is altered with" is not considered formal English. It's better to use alternatives like "is modified by" or "is changed by" in formal contexts to ensure clarity and grammatical correctness.
How can I avoid making mistakes when using "is altered"?
Ensure you're using the correct preposition to indicate the agent of change. Use "by" instead of "with" to show what is causing the alteration, such as "is altered by" rather than "is altered with".
What's the difference between "is altered with" and "is altered by"?
"Is altered with" is grammatically incorrect. "Is altered by" is the correct usage to indicate that something has been changed by a specific cause or agent. The preposition "by" indicates the agent performing the action.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
79%
Authority and reliability
2.8/5
Expert rating
Real-world application tested