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The widely used allele bn2, in addition to its germline defects at the restrictive temperature, is also defective in somatic development and function as glp-4 (bn2 ts )/ glp-4 null displays slow growth, protruding vulva, and bursting at the vulva.
Moreover, ral1 is also defective in auxin sensation and response.
We assume if a box contains at least two defective batteries, then this box is also defective.
From the view point of mathematics, although near defective close eigenvalues are distinct, the characteristic of the system is also defective.
And the idea of God as the centre of a circle with time being represented by the circumference is also defective because of the temporal order is linear and not circular.
For example, FtsZG103S is defective in binding to GTP; hence, is also defective in GTP hydrolysis.
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Unfortunately, the CRIB domain mutant of Cdc42EP3 (Cdc42EP3 IS-AA) was also defective in interaction with actin; because it did not represent a specific loss of function, we excluded this mutant from further analysis.
One patient said, "I was thinking, what other genes are also defective?
"They had to send me several new locks (some of the new stuff was also defective) to get up and running initially.
Consistent with NF-κB activation, phosphorylation of Chk2 and p53 was also defective upon ATM inhibitor treatment (Fig. 1D, lane 3) compared with the control.
These mutant cells were also defective in GPI-anchor biosynthesis, failed to grow, were morphologically altered, and had impaired mitochondrial structure and function, demonstrating the importance of PE in parasite's physiology [50].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com