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To modern joke critics, the key distinction between a good joke and a bad one is supposed to be between "punching up" and "punching down" — taking a cheap shot at someone who is already weaker than you.
Consequently, motor cortical dysfunction in chronic migraine during right finger movement may be more easily compensated for in right-handers, but as the left-hand is already weaker in these subjects, the addition of cortical dysfunction perhaps becomes more apparent during left-handed tasks; in this case in terms of latency.
Given that PBA inhibition is already weaker than activation for KCNQ channels, it should be possible to design second generation boronic acid activators that do not inhibit hERG and other Kv channels.
The Notostraca split is already weaker than the other ones.
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The baby is already weak.
Inheritance tax is already weak.
But unlike in America, religion in Germany is already weak.
Public faith in the courts is already weak and the police are widely distrusted in India.
They could decide the economy is already weak and they should hunker down.
"The market, which is already weak, is dramatically shifting away from stores and toward online," said Colin A. McGranahan, a senior analyst at Sanford C. Bernstein & Company.
However, they are not efficient to localise strain across strike-slip faults in post-orogenic settings when the lower crust is already weak.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com