Interestingly, the synergistic effect of SAD and HvGAMYB transcriptional activators is almost abolished when repressor BPBF, a barley prolamin-box binding factor which is another DOF protein, is present with HvWRKY38.
Similar to SRK1, HRK1 expression is almost abolished in the hog1Δ mutant.
In contrast, we found that Esrrb expression is almost abolished in both the Otx2 CKO and the Crx KO retinas, showing that Esrrb is likely to be regulated directly by Crx and indirectly by Otx2.
In double Dlx1 and Dlx2 null mutants, migration is almost abolished and cells accumulate in the ganglionic eminences (Cobos et al., 2005, 2006, 2007).
First, long-term infusion of endotoxin is sufficient to initiate obesity and insulin resistance in mice, an effect that is almost abolished in CD14 knockout mice (8).
Chronic hyperglycaemia has been shown to profoundly diminish the insulinotropic effect of GIP; that is, the insulinotropic effect is almost abolished in patients with longstanding hyperglycaemia [ 24, 30, 31].
The first-phase insulin response is almost abolished or at least severely blunted in patients with type 2 diabetes (7), although levels of fasting insulin may be higher than normal (8).
It has been shown that months after a single dose of 8 Gy to the young mouse brain, hippocampal neurogenesis is almost abolished, and no recovery was seen over time.
The expression of anthocyanin biosynthetic genes DFR, LDOX, and UF3GT is almost abolished in Arabidopsis coi1 plants [ 51], which points to a molecular link between JA signaling and anthocyanin accumulation.
We have previously shown that basal phosphorylation of MYPT-1 at thr-855 and of MLC20 at ser-19 is unaffected by SU6656 but that basal MYPT-1 phosphorylation at thr-855 is almost abolished by Y27632.
Previous reports have shown that SV priming under brief (1 s) sucrose application is almost abolished in unc-13 s69 unc-13 s69nd severely inhibited in unc-13(e1091) mutants (Richmond et and, 1999; Madiseverelyl., 2005).
