Local control by radiotherapy is advisable in case of incomplete excision, as recurrence may transform into malignant melanoma (Rades et al. 2004).
Pharmacological prophylaxis may be advisable in cases of: Bed confinement Low mobility in patients featuring risk factors.
They will not go out of their way to bite but handling them is not advisable and, if you know they are about in your neighbourhood, a quick check in a long unused pair of shoes or Wellington boot might be advisable in case you step on one.
However, the dynamic range of the technique improves after manual and laser microdissection and may therefore at least be advisable in case of very low tumour content (≤30%), when the MLPA outcome is equivocal or when extensive DCIS is present.
As clinically a dichotomization between normal and amplified suffices and MLPA is relatively unsensitive to tumor content, microdissection before MLPA may not be routinely necessary but may be advisable in case of very low tumor content (≤30%), when MLPA results are equivocal, or when extensive ductal carcinoma in situ is present.
Because of the compressive nature of the stresses distributed along the midpalatal suture in the maxillary protraction therapy simulation, which is opposite to the natural growth transversal tendency, maxillary expansion is advisable in clinical cases.
Furthermore, the application of standardised multiple imputation techniques rather than simple complete cases analysis is advisable in studies with large amounts of missing data [ 57].
Pharmacological prophylaxis with LMWH is advisable in major surgery.
With today's Arctic tourist more apt to shoot a camera than a rifle, people come in summer to watch humpback whales spouting in fjords, narwhals swimming among icebergs and, though a professional armed guide might be advisable in this case, polar bears hunting seals.
Retaining samples below the LOD, for example, by imputing LOD/√ 2 as their value, is advisable only in cases in which < 5 10% of samples are below LOD (Lubin et al. 2004).
