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For clinicians using trials we suggest that when a meta-analysis is not available, a focus on the most precise trial is reasonable provided it is adequately powered.
For clinicians and guideline authors trying to use systematic reviews and trials, we cautiously suggest that when a meta-analysis is not available, then a focus on the most precise trial is reasonable provided it is adequately powered (that is the confidence intervals exclude values that would change the clinical decision) and adequately conducted.
"The market is adequately supplied.
The State Supreme Court reversed, holding that the fee advanced legitimate local purposes that could not be adequately served by reasonable nondiscriminatory alternatives.
The court held that the fee at issue advanced legitimate local purposes that could not be adequately served by reasonable nondiscriminatory alternatives and was therefore valid under the Commerce Clause.
This proposal would allow discrimination against out-of-state producers and retailers if lawmakers can prove that such laws advance "a legitimate local purpose that cannot be adequately served by reasonable nondiscriminatory alternatives".
Were we to ask Qutb whether he would have reasons to support laws that protect a robust right to religious freedom if he were adequately informed and reasonable, surely he would say: no.
It is a myth that these drugs have been adequately studied and that reasonable informed consent is possible.
Although the threshold level of SMN protein necessary to maintain motor neurons has not been adequately determined, it is reasonable to predict that doubling or tripling the amount of full length SMN protein should be sufficient to prevent or diminish clinical progression.
Today, the remaining practical concern is whether chrysotile can be produced and used safely, and if indeed this regulation carries a reasonable assurance that workers are adequately protected.
With one exception [ 24], the studies had reasonable sample sizes and were adequately powered to test differences in their primary outcomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com