Exact(6)
DAT is acutely regulated by protein kinase C (PKC) activation and amphetamine exposure, both of which modulate DAT surface expression by endocytic trafficking.
Hepatic glucokinase activity is acutely regulated by its cellular location.
In addition to phosphorylation, ACC is acutely regulated by allosteric effectors including citrate (reviewed in refs. [ 47, 49]).
SGK1 is a serine/threonine kinase downstream of the phosphatidylinositol 3-kinase (PI3K) cascade and its expression is acutely regulated by serum and glucocorticoids [ 36, 59].
PI-3Kinase activity is acutely regulated and a number of isoforms have been cloned that are activated in response to various stimuli [ 4].
Our studies were undertaken (1) to identify the Nox4 ROS product using a membrane-free, partially purified preparation of Nox4 and (2) to test the hypothesis that Nox4 activity is acutely regulated not by activator proteins or calcium, but by cellular pO2, allowing it to function as an O2 sensor, the output of which is signaling H2O2.
Similar(54)
Recently, it was reported that in bulls secretion of insulin-like peptide 3 (inSL3) in blood occurred in a pulsatile manner and was acutely regulated by LH.
Other genes were acutely regulated (Nadc1, Znt2, Zip4, Cyp27a1, Sult1d1, Gstm3, and Abca1).
Time course studies revealed that some genes were acutely regulated, whereas expression of other genes was only affected after prolonged fasting.
Since the levels of intracellular calcium are acutely regulated by uptake into calcium-storing organelles or extrusion via calcium pumps, this may not be the most likely scenario.
Thus Nox1 and Nox2 are acutely regulated by posttranslational mechanisms such as the phosphorylation of regulatory subunits induced by the activities of agonists.
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