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A hormone called vasopressin, which is active in the brain, leads some voles to stay pair-bonded for life.
Most have concentrated their attention on nicotine, since that drug is active in the brain, but with no great success.
That was more than had been expected, although it is not yet clear how many of that 80% are brain-specific.The second surprise was that any gene which is active in the brain at all tends to be active everywhere.
Dopamine acts directly on the brain's hypothalamus the seat of a person's sex drive.Stimulating resultsBecause apomorphine is active in the brain, some researchers wondered whether it would work to stimulate desire in women.
Nastech of Bothell, Washington, is developing apomorphine to treat erectile dysfunction in men as well as FSD.Because apomorphine is active in the brain, some researchers wondered whether it would work to stimulate desire in women.Another drug to look out for is PT-141.
In squid embryos, they found, the gene is active in the brain, olfactory organs, and the iris and lens of the eye--all places where the protein Pax-6 is needed in mice.
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Then they compared levels of period mRNA, a molecule signaling that the gene is active, in the brains of the bees.
The first surprise was that about 80% of the 21,000 genes in the mouse genome are active in the brain.
The cells started turning on some of the same genes that are active in the brain's neurons and associated glial cells.
4. Combining the enzyme reverse transcriptase with messenger RNA (mRNA) isolated from the body's cells yields complementary DNA (cDNA); these cDNAs are stored as bacterial inserts to provide researchers with a "library" of clones for genes known to be active in the brain, liver, etc.
(All molecules have right- and left-sided mirror images; in ADHD treatment, only the right-sided molecules are active in the brain).
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