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In cases where there is a large magnitude of effect, the level of evidence may be increased by one level, and in cases where there is a very large magnitude of effect, it would be increased by two levels.
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However, there are cases in which there is apparently a very large magnitude of effect, but a deeper insight indicates that e.g. due to variation in the severity of the disease the magnitude of the effect is actually not clear.
If there is efficacy, it is not of a very large magnitude".
"Capital raising is a very large challenge".
The campus is a very large one.
This is a very large number.
At the very least it may be possible to use a volunteer sample to demonstrate the need for action most countries in the world are likely to have salt consumption levels far above the WHO consumption target of <5 g/day, and the likelihood that the selection of a volunteer sample will lead to an under-recording of salt consumption of a very large magnitude is probably fairly small.
David Rothery at the Open University's volcano dynamics group, said: "The magnitude 6.3 earthquake was a very large aftershock following the 3 September magnitude 7.0 earthquake.
As is to be expected with a simulation of this magnitude, there are a very large number of parameters.
He's a very large fellow.
It's a very large club.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com