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Hiring a sitter and putting on real clothes is a significant effort for a new mom.
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Valve initially considered having GLaDOS deliver separate lines to each player, but they found this to be a significant effort for minimal benefit.
Modular megasynthases are usually built of several high molecular mass proteins (several hundreds of kilodaltons), and their synthesis and degradation are a significant effort for the cell.
Recent advances in nondestructive testing techniques can be applied to the task of monitoring field structures, although there is a significant effort necessary to calibrate these methods for sulfate attack-related scenarios.
Fully developing the GeneGIF system would be a significant effort.
This is a significant enforcement effort.
But first, there is a significant rebuilding effort.
The collapse of the enforcement efforts is a significant setback for the Pataki administration, which has often cited its stepped-up inspections and stiff fines as evidence that it was cracking down on abuses.
Therefore, there is a significant need for a continuous prevention effort to reduce alcohol's impact on population health.
Given this is a significant investment for Duke Medicine, a targeted research effort is required to evaluate the qualitative and quantitative benefits (as well as unintended consequences) of this initiative.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com