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26 Whether complex I deficiency is a primary consequence of the disease or a secondary adaption is a question that remains to be addressed.
To examine whether cell invasion is a primary consequence of Src42A activation, or a secondary effect of cell death triggered by elevated Src activity, we expressed the caspase inhibitor p35 to block cell death.
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These data have to be carefully evaluated when used to monitor disease evolution [45], as penetration of death probes might be a primary consequence of membrane permeabilization during isolation rather than a physiological feature of the disease [46].
However, one Glasgow-based study found students (of either sex) strongly expected aggression to be a primary consequence of alcohol use, particularly in males (Crawford, 1984).
The data suggest the possibility that reduction of cell senescence may be a primary consequence of DR which in turn may explain known effects of DR such as improved mitochondrial function and reduced production of reactive oxygen species.
Note that the rapidity of clustering in this case is not only a primary consequence of the small number of atoms but a matter of simplicity in structure.
In those experiments, however, it was not clear whether inhibited angiogenesis was a primary effect of radiation or was a consequence of reduced tumor growth.
While respiratory and cardiovascular morbidity and mortality have been long seen as a primary consequence of high air pollution exposure, evidence emerging in the past decade suggests that the CNS may also be a significant target.
A primary consequence of secondary hyperparathyroidism is the development of renal osteodystrophy, which may manifest as fractures, bone pain and avascular necrosis [ 1].
A primary consequence of Babesia infections are haemostasis disturbances together with inflammation-related complications.
Next, we investigated whether Rnf12 upregulation is a primary, early consequence of Nanog depletion.
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