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This is a paramount aspect to take into account; without this there is no indication that a given AD can maintain its established accuracy profile across chemical space with new data.
Religion is a paramount aspect of human culture.
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The extreme sensitivity surrounding the North Caucasus is definitely a paramount aspect of the work of every professional working in or on this crisis area.
Secrecy is a paramount concern.
The budget obviously is a paramount consideration.
But of course public safety is a paramount concern.
Safety is a paramount concern and addressed in several ways.
Listeria monocytogenes is a paramount example.
Antibiotics resistance is a paramount issue in medical practice.
"It's about somebody who believes that reflective self-consciousness and the identity that that engenders is the paramount aspect of what it means to be a person," he said.
Clinical benefit was narrowly defined using efficacy (PFS/OS) under the prior assumptions that 1) efficacy was the paramount aspect of clinical benefit and 2) the use of PFS instead of OS has been controversial among Canadian HTA experts.
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