Sentence examples for is a marked problem from inspiring English sources
Cytotoxicity often correlates with a high charge density and is a marked problem with highly cationic PAMAM dendrimers.
However, cytotoxicity of highly cationic dendrimers is a marked problem that hinders their widespread use in drug and gene delivery [ 6, 7].
It is characteristic in NPC that a wider irradiation field is required during RT due to its progression pattern, and mucositis is a marked problem even when RT alone is performed.
While, there is a marked decline in the problem since 1998, when mine action commenced, the practice has by no means disappeared in the project areas.
The problem is a marked shift in the economics surrounding the PlayStation and Xbox consoles.
That decision is a marked turnabout from the plant's problems of a few years ago, which produced a fine of $2.1 million, the largest in the history of the United States nuclear power industry.
It has also been shown that for those with mental health problems there is a marked social patterning for hospital admissions.
It is a marked change from a year ago.
The backlight has always been the biggest problem with the original model and this new light is a marked improvement.
The problem would be less severe in East Africa where there is a marked and prolonged dry period, with consequent absence of berries in the field for extended periods.
The problem is so prevalent that in some parts of India there is a marked gender imbalance.
