Sentence examples for is a main effector from inspiring English sources

Obesity is a main effector of BP in children [ 14, 15, 25, 30- 33].

Furthermore, we found that induction of Gadd45 α is a main effector event in apoptosis triggering by Shigella.

Angiotensin II is a main effector peptide in the renin-angiotensin system and plays a very important role in controlling renal homeostasis as a vasoconstrictor.

This cascade is a main effector pathway of ERBB receptors, and altered in a high percentage of cancers usually be mutation of Ras or BRAFgenes.

Angiotensin II (Ang II) is a main effector peptide in the renin angiotensin system and participates in the regulation of vascular tone.

CDKN1A, downregulated by M1775R, is a main effector of cell cycle arrest in response to DNA damage and a promoter of apoptosis [ 28].

Interestingly, a previous study indicated that high glucose was sufficient by itself to induce an autocrine production of TGF- β1 in cultured human peritoneal MCs and could therefore be a main effector of the activation of the Smad-dependent pathway in our culture model that is using a BMe.

For atherosclerosis, elevated lipoprotein levels and cigarette smoke are a main effectors, [ 83] while restenosis is mainly an overshooting wound healing process in response to vascular injury by balloon dilation or stent placement.

P21-activated protein kinase1 (PaK1), a member of group I PAKs, is a main downstream effector of the small Rho GTPases.

β-catenin is a main downstream effector of the canonical Wnt signaling pathway, which has a dual role in EMT: it not only enhances cell-cell adhesion by associating with cadherin complexes in adherent junctions of cell membrane, but also functions as a transcriptional co-activator by interacting with TCF transcription factor complexes in the nucleus [ 42].

Soon after cyclic AMP signaling was implicated as a main effector in the conditioning paradigm, it was demonstrated that intraganglionic injection of a membrane permeable cyclic AMP analog, dibutyryl cyclic AMP (db-cyclic AMP), could mimic the effects of a conditioning lesion and that this effect occurred through activation of PKA [ 20, 52].