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5-Aminolevulinic acid (ALA) is a key precursor in the biosynthesis of all porphyrins compounds, such as Chl, heme, and phytochrome (Eiji et al. 2003).
An L-phenylalanine-overproducing E. coli strain was engineered to enhance the availability of phosphoenolpyruvate (PEP), which is a key precursor in the biosynthesis of aromatic compounds in microbes.
Monacolin J is a key precursor for the synthesis of simvastatin (Zocor), an important drug for treating hypercholesterolemia. Industrially, monacolin J is manufactured through alkaline hydrolysis of lovastatin, a fungal polyketide produced by Aspergillus terreus.
In its simple design and detail it shares many of the characteristics of, and is a key precursor to, Dürer's mature work.
Three Studies for Figures at the Base of a Crucifixion is a key precursor to Bacon's later work, and he sustained its formal and thematic preoccupations throughout his career.
In insects DDC occupies a special position because dopamine is a key precursor in insect cuticle formation [8], [9], eggshell hardening [10], [11] and is involved in immune responses [8], [12], [13], [14], [15], [16], [17].
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Most notably, the "Birmingham sound" (the mid-90s industrial output of Regis, Surgeon and the club House of God) was a key precursor to modern Berlin techno.
It could help in digestion, he speculates, or be a key precursor for other metabolically important chemicals, such as prostaglandins.
A short-term preslip is sometimes thought to be a key precursor of the impending earthquake and has been extensively examined in earthquake cycle simulations (e.g., Kato and Hirasawa 1999; Kato and Tullis 2003).
Paleomagnetic data and tectonic reconstructions of the WSRS region indicate that major Jurassic translation and rotation of microcontinental blocks were a key precursor to Gondwana breakup by seafloor spreading.
This new view also reinforces the critical metabolic node constituted by Glc-1P in the microorganism, as it is a key intermediate in the interconnection between Tre and glycogen metabolisms [28,30,32,33,64], as well as also being a key precursor for the synthesis of mycolic acids derivatives [68,69].
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CEO of Professional Science Editing for Scientists @ prosciediting.com