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These are the cases mentioned previously of the EDF pentapeptide of E. coli which is a functional element of glucose-6-phosphate dehydrogenase and the enterococcus pheromones, which anchor the propeptide to the membrane.
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However, the Ikhwân do not fail to approach policy from a theoretical standpoint and the philosophical doctrines developed in their Epistles can be understood to be a functional element of their political vision.
Most such tools give a quantitative measure of how likely a given sequence is to be a functional element of interest (e.g. transcription factor-binding site), and so simply examining the difference in scores between a mutated sequence and its original sequence can give an idea of the functionality of the mutation.
These studies evoke the idea that localized distribution is a signature of a functional element of the promoter.
The connection between p-loop containing nucleoside triphosphate hydrolase and PEP carboxykinase-like folds via p-loop prototype (Fig. 2) indicates that p-loop as EFL is an essential functional element of enzymes belonging to different superfamilies with different folds.
These findings are consistent with the induction of ATAF2 in response to TMV infection and indicates that the 30-bp binding element is a functional target of endogenously expressed ATAF2.
The coenzyme-binding region is the largest functional element of CapE.
To test whether the identified forkhead element was a functional regulator of the promoter and whether it could explain the increased stimulation of PII −516bp-luciferase by the FOXL2 C134W (Fig. 2) we generated a mutant version of the reporter, in which the putative element was mutated in the same manner as in the EMSA probes above.
However, some SNPs are predicted to be located inside functional elements of ITGAV and part of the region seems to show variation in copy number.
Besides, the Encyclopedia of DNA Elements (ENCODE) project is studying different functional elements of human genome including regions of histone modifications.
Higher persistence length of vertebrate CNC indicates that the conserved information in vertebrates and insects is organized in functional elements of different lengths.
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