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"It is a dire situation.
"It is a dire situation," she said.
"This is a dire crisis," McCain said.
Overcrowding is a dire issue in Maula prison.
There is a dire shortage of cooking gas.
There is a dire need for reform in the kingdom.
There is a dire shortage of the right people".
There is a dire (and confusingly updated) clubbing scene.
Therefore, there is a dire need to find alternative treatment options for this disease.
There is a dire need for novel therapeutics to treat the virulent malarial parasite, Plasmodium falciparum.
Progression of liver fibrosis to cirrhosis is a dire consequence of chronic liver diseases (CLD).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com