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Setting out where he believes the party needs to go in the next decade, he says: "Marx was right – alienation is a central problem in modern society.
This is a central problem in most medical treatment: patients are known and treated as totally separate from the families in which they live.
The attacks by Ms. Palin and Mr. Giuliani highlight what many observers say is a central problem for Mr. Romney as he seeks the nod from Republicans: No matter what he says about the economy and jobs and foreign policy, his rivals have one response: that Mr. Romney was the inspiration for Mr. Obama's health care plan.
This Russian audience (and plenty of foreigners, as well) has often heard from Mr. Putin, in line with a major policy speech he made in Munich in 2007, that an aggressive, overbearing United States is a central problem for the world.
He told BBC Radio 4's The World at One programme: "You can make the argument that senior figures in science have to be first of all aware that there is a central problem of women progressing up to the highest levels of science and secondly, therefore, have to be mindful of that and careful of their language.
Graphical model processing is a central problem in artificial intelligence.
Sensor localization is a central problem for sensor networks.
Protein folding is a central problem in biological physics.
Integrating actions and state constraints is a central problem in knowledge representation.
The definition of concepts is a central problem in commonsense reasoning.
Tracking articulated targets is a central problem in computer vision, with applications including robotics and surveillance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com