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Development of advanced castration-resistant prostate cancer (CRPC) is a biological consequence of lack of an apoptotic response of prostate tumor cells to androgen ablation.
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To find out if the HIF-1α suppression was a biological consequence of HIF-1mRNA inhibition by ABZ, using RT-PCR, the tumor samples were examined for HIF-1mRNA expression.
Differentiation studies were consistent with a biological consequence of these changes.
Consistently, regression of metastatic mutant B-RAF melanomas is a frequent sign of the response to administration of PLX4032, a close analogue to PLX4720, suggesting that induction of apoptosis may be a major biological consequence of inhibition of mutant B-RAF.
Cellular senescence is the biological consequence of aging.
5) What is the biological consequence of the PGBD5 mediated transposition?
Are the helminths Trx-1 not regulated by posttranscriptional modifications, and which is the biological consequence of this? [ 20].
What might be the biological consequence of the differential amplification and significant copy number variation of TCAST2 satellite subfamilies among strains?
There is thus a clear biological consequence of fine-tuning Myc expression in single, activated T cells.
The net result of all these complexities is that the biological consequences of a genetic (or stable epigenetic) change are often both indirect and mixed.
This phenomenon is more likely a common biological consequence of ligament-rupture healing.
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